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TRAP-6-IN-1

CAT: 0804-HY-146333Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146333Size:1 Each
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Description
TRAP-6-IN-1 (Compound 8) is a dual collagen and TRAP-6 inhibitor with IC50 values of 17.12 µM and 11.88 µM against collagen and TRAP-6, respectively. TRAP-6-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner[1].
CAS Number
2068737-10-8
UNSPSC
12352005
Target
Protease Activated Receptor (PAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/trap-6-in-1.html
Solubility
10 mM in DMSO
Smiles
CCC1(CC)C=CC2=O[H]OC3=C2C1=C(C4=C3CC=CC4)O
Molecular Formula
C18H20O3
Molecular Weight
284.35
References & Citations
[1]Méndez D, et al. Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6. Eur J Med Chem. 2020 Apr 15;192:112187.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported