TRAP-6-IN-1

• UNSPSC Description:

  TRAP-6-IN-1 (Compound 8) is a dual collagen and TRAP-6 inhibitor with IC50 values of 17.12 µM and 11.88 µM against collagen and TRAP-6, respectively. TRAP-6-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner[1].

• Target Antigen:

  Protease Activated Receptor (PAR)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/trap-6-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCC1(CC)C=CC2=O[H]OC3=C2C1=C(C4=C3CC=CC4)O

• Molecular Weight:

  284.35

• References & Citations:

  [1]Méndez D, et al. Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6. Eur J Med Chem. 2020 Apr 15;192:112187.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2068737-10-8