TRK-IN-19

TRK-IN-19

• UNSPSC Description: TRK-IN-19 (Compound I-10 ) is a potent inhibitor of TRK (TRKA IC50 = 1.1 nM, TRKAG595R IC50 = 5.3 nM). TRK-IN-19 has the potential for the research of cancer diseases[1].
• Target Antigen: Trk Receptor
• Type: Reference compound
• Related Pathways: Neuronal Signaling;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/trk-in-19.html
• Solubility: 10 mM in DMSO
• Smiles: COC1CCC(CC1)NC(C2=C3N=C(C=CN3N=C2)N(CC4=CC(F)=CC=C4)C)=O
• Molecular Weight: 411.47
• References & Citations: [1]Sun M, et al. Design, synthesis and biological activity of bicyclic carboxamide derivatives as TRK inhibitors. Bioorg Med Chem. 2020 Dec 1;28(23):115811. doi: 10.1016/j.bmc.2020.115811.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported