RyRs activator 2

• Description:

  RyRs activator 2 (compound 7o) is a potent activator of ryanodine receptors (RyRs) . RyRs activator 2 is 30% larvicidal activity, comparable to chlorantraniliprole (30%) and better than cyantraniliprole (10%) [1].

• UNSPSC:

  12352005

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ryrs-activator-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (C1=CC (C (F) (F) F) =NN1C2=CC (C#N) =CC=C2Cl) NC3=C (C (NC (C) C) =O) C=C (Cl) C=C3C

• Molecular Formula:

  C23H18Cl2F3N5O2

• Molecular Weight:

  524.32

• References & Citations:

  [1]Liu J, et al. Discovery of a polysubstituted phenyl containing novel N-phenylpyrazole scaffold as potent ryanodine receptor activator. Bioorg Med Chem. 2020 Dec 15;28 (24) :115829.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2408415-52-9