RyRs activator 2

• Description :

  RyRs activator 2 (compound 7o) is a potent activator of ryanodine receptors (RyRs) . RyRs activator 2 is 30% larvicidal activity, comparable to chlorantraniliprole (30%) and better than cyantraniliprole (10%) [1].

• CAS Number :

  [2408415-52-9]

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/ryrs-activator-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC(C(F)(F)F)=NN1C2=CC(C#N)=CC=C2Cl)NC3=C(C(NC(C)C)=O)C=C(Cl)C=C3C

• Molecular Formula :

  C23H18Cl2F3N5O2

• Molecular Weight :

  524.32

• References & Citations :

  [1]Liu J, et al. Discovery of a polysubstituted phenyl containing novel N-phenylpyrazole scaffold as potent ryanodine receptor activator. Bioorg Med Chem. 2020 Dec 15;28 (24) :115829.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported