RyRs activator 3

CAT: 0804-HY-156082Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-156082Size:1 Each
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Description
RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella) . The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity[1].
CAS Number
[2850333-35-4]
UNSPSC
12352005
Target
Calcium Channel; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ryrs-activator-3.html
Solubility
10 mM in DMSO
Smiles
BrC1=NN(C(C(NC2=C(C=C(C=C2C3=NOC(C3)C(NC4CC4)=O)Cl)C)=O)=C1)C5=NC=CC=C5Cl
Molecular Formula
C23H19BrCl2N6O3
Molecular Weight
578.25
References & Citations
[1]Pang X, et al. Design, Synthesis, and Insecticidal Evaluation of N-Pyridylpyrazole Amide Derivatives Containing 4,5-Dihydroisoxazole Amide as Potential Ryanodine Receptor Activators. J Agric Food Chem. 2023 Sep 20;71 (37) :13688-13695. .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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