RyRs activator 3

• UNSPSC Description:

  RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity[1].

• Target Antigen:

  Calcium Channel; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ryrs-activator-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  BrC1=NN(C(C(NC2=C(C=C(C=C2C3=NOC(C3)C(NC4CC4)=O)Cl)C)=O)=C1)C5=NC=CC=C5Cl

• Molecular Weight:

  578.25

• References & Citations:

  [1]Pang X, et al. Design, Synthesis, and Insecticidal Evaluation of N-Pyridylpyrazole Amide Derivatives Containing 4,5-Dihydroisoxazole Amide as Potential Ryanodine Receptor Activators. J Agric Food Chem. 2023 Sep 20;71(37):13688-13695. .

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2850333-35-4