RyRs activator 3

RyRs activator 3

• CAS Number: 2850333-35-4
• UNSPSC Description: RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity[1].
• Target Antigen: Calcium Channel; Parasite
• Type: Reference compound
• Related Pathways: Anti-infection;Membrane Transporter/Ion Channel;Neuronal Signaling
• Applications: COVID-19-immunoregulation
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/ryrs-activator-3.html
• Solubility: 10 mM in DMSO
• Smiles: BrC1=NN(C(C(NC2=C(C=C(C=C2C3=NOC(C3)C(NC4CC4)=O)Cl)C)=O)=C1)C5=NC=CC=C5Cl
• Molecular Weight: 578.25
• References & Citations: [1]Pang X, et al. Design, Synthesis, and Insecticidal Evaluation of N-Pyridylpyrazole Amide Derivatives Containing 4,5-Dihydroisoxazole Amide as Potential Ryanodine Receptor Activators. J Agric Food Chem. 2023 Sep 20;71(37):13688-13695. .
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported