RyRs activator 1

CAT: 0804-HY-146109Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-146109Size:1 Each
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Description
RyRs activator 1 (compound 7f) is a potent activator of ryanodine receptors (RyRs) . RyRs activator 1 at 0.5 mg/L displays 100% larvicidal activity. The larvicidal activity of RyRs activator 1 is 90% at 0.01 mg/L[1].
CAS Number
[2571579-14-9]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ryrs-activator-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C(F)(F)F)=NN1C2=CC([N+]([O-])=O)=CC=C2C#N)NC3=C(C(NC)=O)C=C(Cl)C=C3C
Molecular Formula
C21H14ClF3N6O4
Molecular Weight
506.82
References & Citations
[1] Liu J, et al. Discovery of a polysubstituted phenyl containing novel N-phenylpyrazole scaffold as potent ryanodine receptor activator. Bioorg Med Chem. 2020 Dec 15;28 (24) :115829
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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