RyRs activator 1

• Description:

  RyRs activator 1 (compound 7f) is a potent activator of ryanodine receptors (RyRs) . RyRs activator 1 at 0.5 mg/L displays 100% larvicidal activity. The larvicidal activity of RyRs activator 1 is 90% at 0.01 mg/L[1].

• UNSPSC:

  12352005

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ryrs-activator-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(C(F)(F)F)=NN1C2=CC([N+]([O-])=O)=CC=C2C#N)NC3=C(C(NC)=O)C=C(Cl)C=C3C

• Molecular Formula:

  C21H14ClF3N6O4

• Molecular Weight:

  506.82

• References & Citations:

  [1] Liu J, et al. Discovery of a polysubstituted phenyl containing novel N-phenylpyrazole scaffold as potent ryanodine receptor activator. Bioorg Med Chem. 2020 Dec 15;28 (24) :115829

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2571579-14-9