PD-1/PD-L1-IN-48
CAT:
804-HY-163837
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PD-1/PD-L1-IN-48
- UNSPSC Description: PD-1/PD-L1-IN-48 (compound HD10) is a potent inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.1 nM. PD-1/PD-L1-IN-48 plays an important role in cancer research[1].
- Target Antigen: PD-1/PD-L1
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-48.html
- Smiles: N#CC1=CN=CC(COC2=CC(OCC3=C(C(C4=CC5=C(OCCO5)C=C4)=CC=C3)C(F)F)=CC=C2CNCCO)=C1
- Molecular Weight: 573.59
- References & Citations: [1]Hua Zhang, et al. Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2'-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors. J Med Chem. 2023 Aug 10;66(15):10579-10603.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported