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PD-1/PD-L1-IN-46

CAT:
804-HY-161748
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
PD-1/PD-L1-IN-46 - image 1

PD-1/PD-L1-IN-46

  • UNSPSC Description:

    PD-1/PD-L1-IN-46 (compound (R)-C27 ) is an PD-1/PD-L1 antagonist with IC50 value of 18.66 nM[1].

  • Target Antigen:

    PD-1/PD-L1

  • Type:

    Reference compound

  • Related Pathways:

    Immunology/Inflammation

  • Field of Research:

    Cancer

  • Assay Protocol:

    https://www.medchemexpress.com/pd-1-pd-l1-in-46.html

  • Smiles:

    ClC1=C(C=CC=C1C2=CC=CC=C2)[C@@H]3OC4=C(CC3)C(OCC5=CC=CN=C5)=C(CNCCO)C=C4Cl

  • Molecular Weight:

    535.46

  • References & Citations:

    [1]Luosen Wang, et al. Design, Synthesis, and Biological Evaluation of Chroman Derivatives as PD-1/PD-L1 Antagonists. J Chem Inf Model. 2024 Jun 24;64(12):4877-4896.

  • Shipping Conditions:

    Room temperature

  • Clinical Information:

    No Development Reported

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