PD-1/PD-L1-IN-38

• UNSPSC Description:

  PD-1/ PD-L1-in-38 is a PD-1/PD-L1 inhibitor, which can inhibit the proliferation of tumor cells, promote the secretion of INF-γ by CD8+ T cells, and inhibit the ability of PD-1/PD-L1 signal transduction. PD-1/PD-L1-IN-38 has antitumor activity[1].

• Target Antigen:

  PD-1/PD-L1

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pd-1-pd-l1-in-38.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC2=C(C3=C(C(C)=C(C=C3)C)C=C2)C4=C1O[C@H](OC(C)=O)[C@H](C5=CC=CC=C5)O4)C

• Molecular Weight:

  440.53

• References & Citations:

  [1]Li Z, et al. Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy. J Med Chem. 2024 Jan 4.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported