PD-1/PD-L1-IN-38

PD-1/PD-L1-IN-38

• UNSPSC Description: PD-1/ PD-L1-in-38 is a PD-1/PD-L1 inhibitor, which can inhibit the proliferation of tumor cells, promote the secretion of INF-γ by CD8+ T cells, and inhibit the ability of PD-1/PD-L1 signal transduction. PD-1/PD-L1-IN-38 has antitumor activity[1].
• Target Antigen: PD-1/PD-L1
• Type: Natural Products
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-38.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C1=CC2=C(C3=C(C(C)=C(C=C3)C)C=C2)C4=C1O[C@H](OC(C)=O)[C@H](C5=CC=CC=C5)O4)C
• Molecular Weight: 440.53
• References & Citations: [1]Li Z, et al. Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy. J Med Chem. 2024 Jan 4.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported