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SOS1-IN-13

CAT: 0804-HY-144967Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144967Size:1 Each
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Description
SOS1-IN-13 is a potent son of sevenless homolog 1 (SOS1) inhibitor with IC50s of 6.5 nM and 327 nM for SOS1 and pERK, respectively. SOS1-IN-13 can be used for researching anticancer[1].
CAS Number
2654741-45-2
UNSPSC
12352005
Target
Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sos1-in-13.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C2C(C(C)=NN=C2N[C@@H](C3=CC=CC(C(F)(F)F)=C3C)C)=C1)OC
Molecular Formula
C21H22F3N3O2
Molecular Weight
405.41
References & Citations
[1]Matthew Arnold Marx, et al. Sos1 inhibitors. WO2021127429A1 (compound 4-1)
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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