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CDK2-IN-9

CAT: 0804-HY-144811Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144811Size:1 Each
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Description
CDK2-IN-9 is a potent CDK2 inhibitor with an IC50 of 0.63 μM. CDK2-IN-9 shows antiproliferative activity. CDK2-IN-9 induces apoptosis and cell cycle arrest at S and G2/M phase. CDK2-IN-9 has the potential for the research of melanoma[1].
CAS Number
[2919216-33-2]
UNSPSC
12352005
Target
Apoptosis; CDK
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk2-in-9.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(Cl)C=C1)(NN2C(COC3=CC=CC=C3)=NC4=C(C=CC=C4)C2=O)=O
Molecular Formula
C21H16ClN3O4S
Molecular Weight
441.89
References & Citations
[1]Mohammed ER, et al. Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :686-700.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2

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