BChE-IN-3

• UNSPSC Description:

  BChE-IN-3 (compound 45a) is a potent, selective, time-dependent and pseudoirreversible BChE inhibitor, with an IC50 of 56.9 nM. BChE-IN-3 also shows marginal and reversible (not time-dependent) inhibition of AChE[1].

• Target Antigen:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bche-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCN(CCC1CCCCCC1)CCC2=CNC3=C2C=CC(OC(N(C)C)=O)=C3

• Molecular Weight:

  427.62

• References & Citations:

  [1]Meden A, et al. From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series. Eur J Med Chem. 2022 Apr 15;234:114248.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported