BChE-IN-3

• Description :

  BChE-IN-3 (compound 45a) is a potent, selective, time-dependent and pseudoirreversible BChE inhibitor, with an IC50 of 56.9 nM. BChE-IN-3 also shows marginal and reversible (not time-dependent) inhibition of AChE[1].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/bche-in-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCN(CCC1CCCCCC1)CCC2=CNC3=C2C=CC(OC(N(C)C)=O)=C3

• Molecular Formula :

  C26H41N3O2

• Molecular Weight :

  427.62

• References & Citations :

  [1]Meden A, et al. From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series. Eur J Med Chem. 2022 Apr 15;234:114248.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  AChE; BChE