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AChE/BuChE-IN-7

CAT: 0804-HY-178141Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178141Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AChE/BuChE-IN-7 is a dual-action inhibitor with an IC50 valueof 0.15 μM for AChE and 0.7 μM for BuChE, SI of 4.7. AChE/BuChE-IN-7 shows anti-oxidant activity and can mitigate H2O2-induced cytotoxicity. AChE/BuChE-IN-7 has genomic stability and prolonged systemic availability. AChE/BuChE-IN-7 can be used for the research of neurological disease, such as Alzheimer's disease[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(N1N=C(C)C=C1C)O[C@H](CC2=CC[C@@]3([H])[C@]4([H])CC5)CC[C@]2(C)[C@@]3([H])CC[C@]4(C)C5=O
Molecular Formula
C25H34N2O3
Molecular Weight
410.55
References & Citations
[1]Nar K, et al. DHEA-carbamate derivatives as dual cholinesterase inhibitors: Integration of enzymatic and biomolecular interactions in Alzheimer's disease. Bioorg Chem. 2025 Sep;164:108901.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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