RIPK1-IN-8

• UNSPSC Description:

  RIPK1-IN-8 (example 16), an aminoimidazopyridine, is a potent and selective RIPK1 inhibitor with an IC50 of 4 nM. RIPK1-IN-8 has the potential for inflammatory diseases research[1].

• Target Antigen:

  RIP kinase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ripk1-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(C2=NN3C(C=C2)=NC(NC(C)=O)=C3)=C(C)N=C1)NCC4=CC(F)=CC(F)=C4OCC5CC5

• Molecular Weight:

  506.50

• References & Citations:

  [1]Michael E. Mertzman, et al. Aminoimidazopyridines as kinase inhibitors. WO2019089442A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2319663-07-3