HER2-IN-9

HER2-IN-9

• UNSPSC Description: HER2-IN-9 is an orally active HER2 inhibitor, with an IC50 value of 0.03 μM. HER2-IN-9 inhibits HER-2 positive breast cancer cells proliferation and migration. HER2-IN-9 can be used in the research of breast cancers[1].
• Target Antigen: EGFR
• Type: Reference compound
• Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/her2-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: FC(F)(C1=CC=C(C=C1)/C=C/C2=COC(CNC3=CC=C(C=C3)Br)=N2)F
• Molecular Weight: 423.23
• References & Citations: [1]Xin-Yang Li, et al. Synthesis and evaluation of novel HER-2 inhibitors to exert anti-breast cancer ability through epithelial-mesenchymal transition (EMT) pathway. Eur J Med Chem. 2022 Jul 5;237:114325.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported