TLR4/NF-κB/MAPK-IN-1

TLR4/NF-κB/MAPK-IN-1

• CAS Number: 2767567-26-8
• UNSPSC Description: TLR4/NF-κB/MAPK-IN-1 is a new type of antineuroinflammatory agent by suppressing TLR4/NF-kB/MAPK pathways.
• Target Antigen: NF-κB; p38 MAPK; Toll-like Receptor (TLR)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;MAPK/ERK Pathway;NF-κB
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/tlr4-nf-κb-mapk-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: C=C1C(O[C@@H]2CC(CBr)=C([C@H]([C@H]12)OC(C)=O)[C@H](CCCOC(C)=O)C)=O
• Molecular Weight: 429.30
• References & Citations: [1]Tang JJ, et al. 1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways. Eur J Med Chem. 2021 Nov 15;224:113713.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported