TLR4/NF-κB/MAPK-IN-1

• UNSPSC Description:

  TLR4/NF-κB/MAPK-IN-1 is a new type of antineuroinflammatory agent by suppressing TLR4/NF-kB/MAPK pathways.

• Target Antigen:

  NF-κB; p38 MAPK; Toll-like Receptor (TLR)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation;MAPK/ERK Pathway;NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/tlr4-nf-κb-mapk-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C=C1C(O[C@@H]2CC(CBr)=C([C@H]([C@H]12)OC(C)=O)[C@H](CCCOC(C)=O)C)=O

• Molecular Weight:

  429.30

• References & Citations:

  [1]Tang JJ, et al. 1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways. Eur J Med Chem. 2021 Nov 15;224:113713.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2767567-26-8