TLR4-IN-1

CAT: 0804-HY-163998Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-163998Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

TLR4-IN-1 (compound 3k) inhibits the cell viability of RAW264.7 with an IC50 of 1.02 μM. TLR4-IN-1 inhibits the release of cytokine TNF-α, IL-1β and IL-6, and exhibits anti-inflammatory efficacy in rats rheumatoid arthritis models[1].

CAS Number

2617578-93-3

UNSPSC

12352211

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tlr4-in-1.html

Smiles

O=C1C(C(C)CC1C(CC(C)=O)=O)=O

Molecular Formula

C10H12O4

Molecular Weight

196.20

References & Citations

[1]Zhou S, et al., Design, Synthesis, and Antirheumatoid Arthritis Mechanism of TLR4 Inhibitors. ACS Omega. 2024 Aug 14;9 (34) :36232-36241.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-168710-01	TLR4/NF-κB-IN-1
HY-142963	TLR4/NF-κB/MAPK-IN-1
HY-107575-01	TLR4-IN-C34
HY-173388	TLR4-IN-2
HY-174524	Human TLR4 mRNA
HY-P73586	TLR4, Human (sf9, His)
HY-W092043-01	TLR4-IN-C34-C2-COOH
HY-P73586Y-01	TLR4, Human (sf9, His, Solution)
HY-RS14587	Tlr4 Mouse Pre-designed siRNA Set A
HY-RS14586	TLR4 Human Pre-designed siRNA Set A

Alternative Products

Catalog	Name
GTR19239336-01	TLR4-IN-1
BA6304-50	MD2-TLR4-IN-1
T80978-01	TLR4 agonist-1
sc-52962	TLR4 (76B357.1)
NBP3-08732CL1	Rabbit Monoclonal TLR4 Antibody (TLR4/3895R) [CoraFluor 1]
bs-7141C-01	TLR4-C34, a TLR4 inhibitor.
33-472	TLR4 Antibody [TLR4/230]
337314-01	TLR4

TLR4-IN-1

Related Products

Alternative Products

Popular Products