NF-κB/PON1-IN-1

NF-κB/PON1-IN-1

• CAS Number: 2419107-97-2
• UNSPSC Description: NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 µM) and hepatoprotective activities[1].
• Target Antigen: NF-κB; Reactive Oxygen Species
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/nf-κb-pon1-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=NC=CN=C1)CSC(N2C3=CC=C(S(=O)(N)=O)C=C3)=NC4=C(C=CC=C4)C2=O
• Molecular Weight: 468.51
• References & Citations: [1]Soliman AM, et al. Antioxidant activity of novel quinazolinones bearing sulfonamide: Potential radiomodulatory effects on liver tissues via NF-κB/ PON1 pathway. Eur J Med Chem. 2020 Jul 1;197:112333.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported