ATR-IN-8

ATR-IN-8

• CAS Number: 2672511-20-3
• UNSPSC Description: ATR-IN-8 is a potent inhibitor of ATR. ATR is a key enzyme in the homologous recombination repair pathway and belongs to the PIKK family. ATR-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021143821A1, compound 3)[1].
• Target Antigen: ATM/ATR
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atr-in-8.html
• Solubility: 10 mM in DMSO
• Smiles: N=S1(C2(CC2)C3=NC(C4=C5C(NC=C5)=NC=C4)=NC(N6[C@@H](COCC6)C)=C3C1)=O
• Molecular Weight: 410.49
• References & Citations: [1]Li Xin, et al. Thickened heteroaryl derivatives, their preparation methods and their application in medicine. Patent WO2021143821A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported