BRD4-IN-3

• Description:

  BRD4-IN-3 (compound 141) is a potent BRD4 inhibitor with an IC50 of 50 value of >1 µM[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315-H319-H335

• Target:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/brd4-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N)C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C3=CC(Cl)=CC=C3C4=C1ON=C4C

• Molecular Formula:

  C20H15Cl2N3O2

• Molecular Weight:

  400.26

• Precautions:

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Brian K. Albrecht, et al. Bromodomain inhibitors and uses thereof. WO2012075383A2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  BRD4

• CAS Number:

  [1380087-86-4]