DC-BPi-11

DC-BPi-11

• CAS Number: 2758411-61-7
• UNSPSC Description: DC-BPi-11 is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC50 value of 698 nM. DC-BPi-11 shows remarkable inhibition against leukemia cell proliferation[1].
• Target Antigen: Epigenetic Reader Domain
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dc-bpi-11.html
• Solubility: 10 mM in DMSO
• Smiles: CN(C)CCCN1C=CC2=C1C=CC(C3=NC(S(C)(=O)=O)=NC4=C3C=CN4)=C2
• Molecular Weight: 397.49
• References & Citations: [1]Lu T, et al. Discovery of High-Affinity Inhibitors of the BPTF Bromodomain. J Med Chem. 2021 Aug 26;64(16):12075-12088.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported