RegisterLogin

BPI-9016M

CAT: 0804-HY-114356-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-114356-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
BPI-9016M is a potent, orally active, and selective dual c-Met and AXL tyrosine kinases inhibitor. BPI-9016M suppresses tumor cell growth, migration and invasion of lung adenocarcinoma[1][2].
CAS Number
[1528546-94-2]
Product Name Alternative
Trimethoprim 3-N-oxide
UNSPSC
12352005
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bpi-9016m.html
Purity
97.13
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CNC=C(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C5C(NCC5)=NC=C4)C(F)=C3
Molecular Formula
C25H18F2N4O3
Molecular Weight
460.43
References & Citations
[1]Zhang P, et al. BPI-9016M, a c-Met inhibitor, suppresses tumor cell growth, migration and invasion of lung adenocarcinoma via miR203-DKK1. Theranostics. 2018 Nov 12;8 (21) :5890-5902.|[2]Hu X, et al. First-in-human phase I study of BPI-9016M, a dual MET/Axl inhibitor, in patients with non-small cell lung cancer.J Hematol Oncol. 2020 Jan 16;13 (1) :6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 1

Related Products

CatalogName
HY-164464-01BPI-15086
HY-178697DC-BPi-07
HY-150211-01DC-BPi-03
HY-141703DC-BPi-11
HY-P83323-01BPI Antibody (YA3068, Rabbit)
HY-141703A-01DC-BPi-11 (hydrochloride)
HY-P7644-01BPI, Human (HEK293, His)
HY-RS01580BPI Human Pre-designed siRNA Set A
HY-RS18324Bpi Mouse Pre-designed siRNA Set A
HY-RS24802Bpi Rat Pre-designed siRNA Set A

Alternative Products

CatalogName
BA8886-5BPI-9016M
556577-01BPI
YP-W29948-01Mouse BPI (BPI) ELISA Kit
MBS8505506-01BPI Antibody
556579-01BPI (FITC)
556578-01BPI (Biotin)
MBS319910-01BPI Protein
C15139-01BPI-460372
556580-01BPI (HRP)
DF7282-BPBPI Peptide

Popular Products