DC-BPi-03

• Description:

  DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC50 of 698.3 nM and a Kd of 2.81 μM[1].

• UNSPSC:

  12352005

• Target:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dc-bpi-03.html

• Purity:

  99.77

• Solubility:

  DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles:

  O=S (C1=NC (C2=CC3=C (NC=C3) C=C2) =CC (NC) =N1) (C) =O

• Molecular Formula:

  C14H14N4O2S

• Molecular Weight:

  302.35

• References & Citations:

  [1]Tian Lu, et al. Discovery of High-Affinity Inhibitors of the BPTF Bromodomain. J Med Chem. 2021 Aug 26;64 (16) :12075-12088.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2758411-46-8