DC-BPi-03

• Description :

  DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC50 of 698.3 nM and a Kd of 2.81 μM[1].

• CAS Number :

  [2758411-46-8]

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/dc-bpi-03.html

• Purity :

  99.77

• Solubility :

  DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles :

  O=S(C1=NC(C2=CC3=C(NC=C3)C=C2)=CC(NC)=N1)(C)=O

• Molecular Formula :

  C14H14N4O2S

• Molecular Weight :

  302.35

• References & Citations :

  [1]Tian Lu, et al. Discovery of High-Affinity Inhibitors of the BPTF Bromodomain. J Med Chem. 2021 Aug 26;64 (16) :12075-12088.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported