DC-015

• Description :

  DC-015 is a selective and orally active alpha 1-adrenoceptor antagonist on plasma lipid and vascular reactivity in hyperlipidaemic rodent model. DC-015 is a synthesized quinazoline derivative. DC-015 decreases mean arterial pressure in rats. DC-015 has antihypertensive activity[1].

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C1NC2=C(C=CC=C2)C3=NCC(CN4CCN(C5=CC=CC=C5OC)CC4)N13

• Molecular Formula :

  C22H25N5O2

• Molecular Weight :

  391.47

• References & Citations :

  [1]Sheu, J. R., et al., (1996) . Effects of DC-015, a novel potent and selective alpha 1-adrenoceptor antagonist on plasma lipid and vascular reactivity in hyperlipidaemic rats. Clinical and experimental pharmacology & physiology, 23 (3), 207-213.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [149847-87-0]