PRMT5-IN-11

• UNSPSC Description:

  PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/prmt5-in-11.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC[C@@H]1[C@@]([C@H]2O)(CC1)O[C@](N3C4=NC=NC(N)=C4N=C3)([H])[C@@H]2O

• Molecular Weight:

  307.31

• References & Citations:

  [1]Jouffroy L, et al. Regio- and Stereoselective Synthesis of C-4' Spirocyclobutyl Ribofuranose Scaffolds and Their Use as Biologically Active Nucleoside Analogues. Org Lett. 2021 Nov 19;23(22):8828-8833.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2567564-33-2