2'-Ethyl Simvastatin

• UNSPSC Description:

  2'-Ethyl Simvastatin (compound 6) is a Mevinolin analog, with HMG-CoA reductase inhibition[1].

• Target Antigen:

  HMG-CoA Reductase (HMGCR)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/2-ethyl-simvastatin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)C(O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(O3)=O)[C@@]12[H])=O

• Molecular Weight:

  390.51

• References & Citations:

  [1]AGGARWAL, D., et al. A quantitative structure-activity relationship study of 3-hydroxy-3methylglutaryl-coenzyme A reductase inhibitors. Journal of Pharmacobio-Dynamics, 1988;11(9), 591–599.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  79902-42-4