3'-Hydroxy simvastatin

• Description :

  3'-Hydroxy simvastatin is a metabolite of simvastatin. Simvastatin (HY-17502) is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) (Ki: 0.2 nM) [1].

• UNSPSC :

  12352005

• Target :

  Drug Metabolite

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Smiles :

  [H][C@@]1([C@H](C=CC2=C[C@@H](C[C@@H]([C@@]21[H])OC(C(C)(C(O)C)C)=O)C)C)CC[C@@]3([H])OC(C[C@@H](C3)O)=O

• Molecular Formula :

  C25H38O6

• Molecular Weight :

  434.57

• References & Citations :

  [1]Slater EE, et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs. 1988;36 Suppl 3:72-82.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1283861-33-5]