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Risperidone E-oxime

CAT: 0804-HY-135194Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-135194Size:1 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Risperidone E-oxime is an impurity of Risperidone[1]. Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively [2][3].
CAS Number
[691007-09-7]
UNSPSC
12352005
Hazard Statement
H302
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/risperidone-e-oxime.html
Solubility
10 mM in DMSO
Smiles
O=C1C(CCN2CCC(/C(C3=CC=C(F)C=C3F)=N\O)CC2)=C(C)N=C4N1CCCC4
Molecular Formula
C23H28F2N4O2
Molecular Weight
430.49
Precautions
P264-P270-P330-P501
References & Citations
[1]Pavel Slanina, et al. Process for making risperidone and intermediates therefor. US20040097523A1.|[2]Nyberg S, et al. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology (Berl) . 1993;110 (3) :265-72.|[3]Zhu HJ, et al. Risperidone and paliperidone inhibit p-glycoprotein activity in vitro. Neuropsychopharmacology. 2007 Apr;32 (4) :757-64.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor

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