Inosine oxime

• Description:

  Inosine oxime (6-Hydroxyadenosine) is an endogenous metabolite in the course of cell metabolism by cytochrome P450, by oxidative stress or by deviating nucleotide biosynthesis. Inosine oxime has toxic and mutagenic for procaryotic and eucaryotic cells[1][2].

• Product Name Alternative:

  6-Hydroxyadenosine

• UNSPSC:

  12352005

• Target:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/inosine-oxime.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@] (O[C@@H] ([C@H]1O) CO) ([H]) N2C3=C (/C (N=CN3) =N/O) N=C2

• Molecular Formula:

  C10H13N5O5

• Molecular Weight:

  283.24

• References & Citations:

  [1]Plitzko B, et, al. The pivotal role of the mitochondrial amidoxime reducing component 2 in protecting human cells against apoptotic effects of the base analog N6-hydroxylaminopurine. J Biol Chem. 2015 Apr 17;290 (16) :10126-35.|[2]Krompholz N, et, al. The mitochondrial Amidoxime Reducing Component (mARC) is involved in detoxification of N-hydroxylated base analogues. Chem Res Toxicol. 2012 Nov 19;25 (11) :2443-50.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  3414-62-8