Inosine oxime

• Description :

  Inosine oxime (6-Hydroxyadenosine) is an endogenous metabolite in the course of cell metabolism by cytochrome P450, by oxidative stress or by deviating nucleotide biosynthesis. Inosine oxime has toxic and mutagenic for procaryotic and eucaryotic cells[1][2].

• Product Name Alternative :

  6-Hydroxyadenosine

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/inosine-oxime.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@H]1[C@](O[C@@H]([C@H]1O)CO)([H])N2C3=C(/C(N=CN3)=N/O)N=C2

• Molecular Formula :

  C10H13N5O5

• Molecular Weight :

  283.24

• References & Citations :

  [1]Plitzko B, et, al. The pivotal role of the mitochondrial amidoxime reducing component 2 in protecting human cells against apoptotic effects of the base analog N6-hydroxylaminopurine. J Biol Chem. 2015 Apr 17;290 (16) :10126-35.|[2]Krompholz N, et, al. The mitochondrial Amidoxime Reducing Component (mARC) is involved in detoxification of N-hydroxylated base analogues. Chem Res Toxicol. 2012 Nov 19;25 (11) :2443-50.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [3414-62-8]