Risperidone (Standard)

CAT: 0804-HY-11018R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-11018R-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Risperidone (Standard) is the analytical standard of Risperidone. This product is intended for research and analytical applications. Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
CAS Number
[106266-06-2]
Product Name Alternative
R 64 766 (Standard)
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor; P-glycoprotein; Reference Standards
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/risperidone-standard.html
Solubility
10 mM in DMSO
Smiles
O=C1C(CCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)=C(C)N=C5N1CCCC5
Molecular Formula
C23H27FN4O2
Molecular Weight
410.48
References & Citations
[1]Nyberg S, et al. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology (Berl) . 1993;110 (3) :265-72.|[2]Chen ML, et al. Risperidone modulates the cytokine and chemokine release of dendritic cells and induces TNF-α-directed cell apoptosis in neutrophils. Int Immunopharmacol. 2012 Jan;12 (1) :197-204.|[3]Zhu HJ, et al. Risperidone and paliperidone inhibit p-glycoprotein activity in vitro. Neuropsychopharmacology. 2007 Apr;32 (4) :757-64.|[4]Bardgett ME, et al. Adult rats treated with risperidone during development are hyperactive. Exp Clin Psychopharmacol. 2013 Jun;21 (3) :259-67.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Launched
Isoform
5-HT2 Receptor

Related Products

CatalogName
HY-135194RRisperidone E-oxime (Standard)
HY-11018-01Risperidone
HY-11018BRisperidone (mesylate)
HY-11018S2-01Risperidone-d6
HY-110232-01Risperidone-d4
HY-11018ARisperidone (hydrochloride)
HY-11018S1Risperidone-d4-1
HY-135194Risperidone E-oxime
HY-A0019BS-01(R) -9-Hydroxy Risperidone-d4
HY-B0204R-01Pimobendan (Standard)

Alternative Products

CatalogName
RM-R191600-01Risperidone
RM-R191614-01Risperidone Impurity 14 (Bicyclo Risperidone)

Popular Products