NO2-SPP

• Description:

  NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC) .

• UNSPSC:

  12352203

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/no2-spp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(SSC1=NC=C([N+]([O-])=O)C=C1)CCC(ON2C(CCC2=O)=O)=O

• Molecular Formula:

  C14H15N3O6S2

• Molecular Weight:

  385.42

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

• References & Citations:

  [1]Qiming Chen, et al. Anti-integrin immunoconjugates, methods and uses. WO2006062779A2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Cleavable Linker; Disulfide Cleavable Linker

• CAS Number:

  663598-61-6