Products for Research Use Only
RegisterLogin

SPP-DM1

CAT: 0804-HY-126491-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-126491-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SPP-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].
CAS Number
452072-20-7
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/spp-dm1.html
Purity
96.29
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCSSC(C)CCC(ON5C(CCC5=O)=O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
Molecular Formula
C44H59ClN4O14S2
Molecular Weight
967.54
References & Citations
[1]Manu Lopus et al. Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Maytansinoids

Related Products

CatalogName
HY-128926-01SPP
HY-132250-01MCC-DM1
HY-48703-01DM1 Impurity
HY-147050Ahx-DM1
HY-101070-01SMCC-DM1
HY-100128-01DM1-SMe
HY-128951-01AMCC-DM1
HY-136286-01MC-DM1
HY-129367NO2-SPP
HY-163548-01SPP-002

Alternative Products

CatalogName
BA2673-1SPP-DM1
BA2428-100SPP
abx411232Clostridium spp. (C. spp.) Antibody
BA2628-1SMCC-DM1
BA2343-50DM1-SMe
123212Mertansine (DM1)
T205771-01SPDB-DM1
T38493MCC-DM1
GTR19189703-01MC-DM1
GTR19253103-01DM1 Impurity

Popular Products