LysoFP-NO2

• UNSPSC Description:

  LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. LysoFP-NO2 is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 μM.

• Target Antigen:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  others

• Assay Protocol:

  https://www.medchemexpress.com/lysofp-no2.html

• Smiles:

  O=C1N(CCN2CCOCC2)C(C3=CC([N+]([O-])=O)=CC4=CC=CC1=C34)=O

• Molecular Weight:

  355.34

• References & Citations:

  [1]Dhara, et al. A new lysosome-targetable turn-on fluorogenic probe for carbon monoxide imaging in living cells. Anal. Chem. 90(4), 2933-2938 (2018).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  69408-75-9