SPP

• Product Name Alternative:

  N-succinimidyl 4-(2-pyridyldithio) pentanoate

• UNSPSC Description:

  SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate[1].

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/spp.html

• Purity:

  97.65

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(SSC1=NC=CC=C1)CCC(ON2C(CCC2=O)=O)=O

• Molecular Weight:

  340.426

• References & Citations:

  [1]Widdison W, et al. Metabolites of antibody-maytansinoid conjugates: characteristics and in vitro potencies. Mol Pharm. 2015 Jun 1;12(6):1762-73.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  341498-08-6