PD-1-IN-22

CAT: 0804-HY-128605Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-128605Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PD-1-IN-22 is a potent programmed cell death-1 (PD-1) /programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM[1].

CAS Number

2349372-98-9

UNSPSC

12352005

Target

PD-1/PD-L1

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pd-1-in-22.html

Purity

98.99

Solubility

10 mM in DMSO

Smiles

CC1=C(NC(C2=CC(CNCCO)=CN3C2=NN=C3)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4

Molecular Formula

C25H25N5O4

Molecular Weight

459.50

References & Citations

[1]Qin M, et al. Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2019 May 9;62 (9) :4703-4715.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-145773	PD-1/PD-L1-IN-22
HY-160585	PD-L1/PD-1-IN-1
HY-158052	PD-1/PD-L1 antagonist 1
HY-144649	PD-1/PD-L1-IN-24
HY-168078	PD-1/PD-L1-IN-50
HY-144447	PD-1/PD-L1-IN-17
HY-169190	PD-1/PD-L1-IN-53
HY-132202-01	PD-1/PD-L1-IN-10
HY-144442	PD-1/PD-L1-IN-15
HY-129172A	PD-1/PD-L1-IN 5

Alternative Products

Catalog	Name
MBS3842898-01	PD-1-IN-22
T63607-01	PD-1/PD-L1-IN-22
A18434-100	PD-1-IN-22 100mg
A18434-50	PD-1-IN-22 50mg
A18434-25	PD-1-IN-22 25mg
A18434-5	PD-1-IN-22 5mg
A18434-500	PD-1-IN-22 500mg
A18434-1	PD-1-IN-22 1mg
A18434-10	PD-1-IN-22 10mg
A18434-2	PD-1-IN-22 2mg

PD-1-IN-22

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