PD-1/PD-L1-IN-22

PD-1/PD-L1-IN-22

• CAS Number: 2159063-12-2
• UNSPSC Description: PD-1/PD-L1-IN-22 (Example 2) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-22 blocks PD-1/PD-L1 with the IC50 of 0.732 μM. PD-1/PD-L1-IN-22 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
• Target Antigen: PD-1/PD-L1
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-22.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C)NCCNCC1=CC(Cl)=C(C=C1OC)OCC2=CC=CC(C3=CC=CC=C3)=C2Br
• Molecular Weight: 517.84
• References & Citations: [1]Phenylate derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202276A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported