ENMD-1068 (hydrobromide)

• UNSPSC Description:

  ENMD-1068 hydrobromide is a potent PAR2 antagonist. ENMD-1068 hydrobromide attenuates joint inflammation in a dose-dependent manner. ENMD-1068 hydrobromide can be used in research of joint inflammation[1].

• Target Antigen:

  Protease Activated Receptor (PAR)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/enmd-1068-hydrobromide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCN(C(CC(C)C)=O)CC1)CCCCCN.Br

• Molecular Weight:

  364.32

• References & Citations:

  [1]Kelso EB, et, al. Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation. J Pharmacol Exp Ther. 2006 Mar;316(3):1017-24.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  644961-61-5