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Mindeudesivir (hydrobromide)

CAT: 0804-HY-145119AS-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145119AS-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mindeudesivir (JT001; VV116; GS-621763-d1) hydrobromide is a deuterated version of Remdesivir , a highly orally active nucleoside antiviral against SARS-CoV-2 and respiratory syncytial virus (RSV). Mindeudesivir hydrobromide retains the antiviral activity of Remdesivir against COVID-19, and is the first domestically produced deuterium targeting the COVID-19[1][2].
CAS Number
2779498-79-0
Product Name Alternative
VV116; GS-621763-d1 (hydrobromide)
UNSPSC
12352005
Target
Influenza Virus; RSV; SARS-CoV
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
98.16
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
[H]Br.N#C[C@](O[C@@H]1COC(C(C)C)=O)(C2=CC([2H])=C3N2N=CN=C3N)[C@@H]([C@@H]1OC(C(C)C)=O)OC(C(C)C)=O
Molecular Formula
C24H31DBrN5O7
Molecular Weight
583.45
References & Citations
[1]Zhang R, et al. Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model. Signal Transduct Target Ther. 2022;7 (1) :123. Published 2022 Apr 16.|[2]Qian HJ, et al. Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects [published online ahead of print, 2022 Mar 16]. Acta Pharmacol Sin. 2022;1-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
Phase 3

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