KMG-1068

• Target :

  Molecular Glues

• Related Pathways :

  PROTAC

• Bioactivity :

  KMG-1068 (Compound 4a), a molecular glue, acts as a GSPT1/2 degrader. By binding to the IMiD binding site on CRBN, KMG-1068 efficiently induces CRBN-dependent degradation of GSPT1/2 and facilitates the formation of a ternary complex with GSPT1/2. KMG-1068 holds potential for use in cancer research.

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C