U-44069

• Description :

  U-44069 is a stable prostaglandin (PG) H2 analogue and a potent vasoconstrictor. U-44069 induces Ca influx at preglomerular vessels[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H225, H319, H336

• Target :

  Prostaglandin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/u-44069.html

• Concentration :

  28.53 mM * 100 μL in Methyl acetate

• Purity :

  98.0

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(CCC/C=C\C[C@@H]1[C@H]([C@@]2([H])C[C@]1([H])OC2)/C=C/[C@@H](O)CCCCC)=O

• Molecular Formula :

  C21H34O4

• Molecular Weight :

  350.49

• Precautions :

  H225, H319, H336

• References & Citations :

  [1]Simpson AW, et, al. Low concentrations of the stable prostaglandin endoperoxide U44069 stimulate shape change in quin2-loaded platelets without a measurable increase in [Ca2+]i. FEBS Lett. 1986 Jun 9;201 (2) :301-5.|[2]Loutzenhiser R, et, al. Reversal of renal and smooth muscle actions of the thromboxane mimetic U-44069 by diltiazem. Am J Physiol. 1986 Apr;250 (4 Pt 2) :F619-26.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Solution, -20°C, 2 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [56985-32-1]