BMS-929075

• Description :

  BMS-929075 is a potent and orally active HCV NS5B replicase palm site allosteric inhibitor. BMS-929075 shows high oral bioavailability. BMS-929075 shows cytotoxicity[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  HCV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/bms-929075.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC(C2=C(F)C3=C(OC(C4=CC=C(F)C=C4)=C3C(NC)=O)C=C2)=C(C)C=C1)NC5(CC5)C6=NC=CC=N6

• Molecular Formula :

  C31H24F2N4O3

• Molecular Weight :

  538.54

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Yeung KS, et al. Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. J Med Chem. 2017 May 25;60 (10) :4369-4385.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [1217338-97-0]