PF-03246799

CAT: 0804-HY-119103Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-119103Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PF-03246799 is a potent and selective 5-HT2C receptor agonist with an EC50 of 190 nM and a Ki of 160 nM. PF-03246799 shows selectivity for 5-HT2C over 5-HT2A and 5-HT2B receptors. PF-03246799 has the potential for stress urinary incontinence (SUI) research[1].
CAS Number
[1065110-62-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pf-03246799.html
Solubility
10 mM in DMSO
Smiles
C12=NC(CC3=CC=CC=C3)=NC=C1CCNCC2
Molecular Formula
C15H17N3
Molecular Weight
239.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Andrews MD, et al. Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence. Bioorg Med Chem Lett. 2011 May 1;21 (9) :2715-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor

Related Products

CatalogName
HY-123854-01PF-06426779
HY-15426-01PF-04957325
HY-112855-01PF-06454589
HY-19562-01PF-06260933
HY-19321-01PF-06282999
HY-100181-01PF-04991532
HY-12942-01PF-05175157
HY-10459-01PF-562271
HY-108341-01PF-06424439
HY-10461-01PF-573228

Alternative Products

CatalogName
M10282-01PF-03246799
MBS5814043PF-03246799 hydrochloride
MBS579460PF-03084014 (PF-3084014)
MBS3602700-01PF-06651600
MBS3613167-01PF-9601N
MBS3601321-01PF-04995274
MBS3601039-01PF-4708671
MBS3600407-01PF-04620110
MBS3601851-01PF-06282999
MBS3602138-01PF-06447475

Popular Products