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PF-08046054

CAT: 0804-HY-171821-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-171821-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-08046054 (SGN-PDL1V) is a PD-L1-directed antibody-drug conjugate (ADC), which is comprised of an anti-PD-L1 antibody conjugated to the vedotin drug-linker, VcMMAE. PF-08046054 is direct cytotoxicity to PD-L1-expressing tumor cells via the intracellular delivery of MMAE. PF-08046054 can be used for the study of solid tumors[1].
Product Name Alternative
SGN-PDL1V
UNSPSC
12352203
Target
Antibody-Drug Conjugates (ADCs) ; Microtubule/Tubulin; PD-1/PD-L1
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
97.41
Smiles
[PF-08046054]
Molecular Weight
150166 (average)
References & Citations
[1]Byron Kwan, et al. 783 SGN-PDL1V, a novel, investigational PD-L1-directed antibody-drug conjugate for the treatment of solid tumors Free. Regular and Young Investigator Award Abstracts. Immuno-Conjugates and Chimeric Molecules.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
ADC Related
Clinical Information
No Development Reported

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