SC-22716

• Description:

  SC-22716 is a potent, competitive, reversible inhibitor of human LTA4 hydrolase, with an IC50 of 0.20 µM. SC-22716 has potential for the research of inflammatory bowel disease (IBD) and psoriasis[1].

• UNSPSC:

  12352005

• Target:

  Aminopeptidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sc-22716.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N1(CCCC1)CCOC2=CC=C(C=C2)C3=CC=CC=C3

• Molecular Formula:

  C18H21NO

• Molecular Weight:

  267.37

• References & Citations:

  [1]Penning TD, et, al. Structure-activity relationship studies on 1-[2- (4-Phenylphenoxy) ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A (4) (LTA (4) ) hydrolase. J Med Chem. 2000 Feb 24;43 (4) :721-35.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [262451-89-8]