SC-77964

• Description :

  SC-77964 is a potent, selective and orally active matrix metalloprotease (MMP) inhibitor. SC-77964 shows IC50 values [1].

• UNSPSC :

  12352005

• Target :

  MMP

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer; Inflammation/Immunology

• Smiles :

  O=C(C1(S(=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O)CCN(C4CC4)CC1)NO

• Molecular Formula :

  C22H23F3N2O6S

• Molecular Weight :

  500.49

• References & Citations :

  [1]Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease J. Med. Chem., Article ASAP Publication Date (Web) : August 20, 2010|[2]Lutz MR Jr, et al. Carborane-Containing Matrix Metalloprotease (MMP) Ligands as Candidates for Boron Neutron-Capture Therapy (BNCT) . ChemMedChem. 2020 Oct 19;15 (20) :1897-1908.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MMP-13; MMP-2; MMP-9

• CAS Number :

  [308824-37-5]