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FR260010 (free base)

CAT: 0804-HY-118450Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118450Size:1 Each
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Description
FR260010 free base is a selective 5-HT2C receptor antagonist, with a Ki value of 1.1 nM[1].
CAS Number
374555-75-6
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fr260010-free-base.html
Solubility
10 mM in DMSO
Smiles
CC1=CN(C=N1)C2=CC(NC3=C4CCC5=CC=CC=C5C4=NC=N3)=CC=C2
Molecular Formula
C22H19N5
Molecular Weight
353.42
References & Citations
[1]Katsuya Harada, et al. Activation of the serotonin 5-HT2C receptor is involved in the enhanced anxiety in rats after single-prolonged stress. Pharmacol Biochem Behav. 2008 Mar;89 (1) :11-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor