SW116 (free base)

• UNSPSC Description:

  SW116 free base is a selective fluorescent ligand for sigma-2 receptor with a Ki of 14 nM. SW116 free base exhibits in methanol a maximal excitation wavelength of 333 nM, and a maximal emission wavelength of 506 nM. SW116 free base can be internalized into MDA-MB-435 cells, and reach 50% maximum fluorescent intensity in 24 minutes. SW116 free base can be as a fluorescent probe used in cancer research[1].

• Target Antigen:

  Sigma Receptor

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sw116-free-base.html

• Smiles:

  O=[S](NCCCCCCCCCCN([C@]1([H])C2)[C@@](CCC1)([H])C[C@@H]2OC(NC(C=C3C)=C(C=C3)OC)=O)(C4=CC=CC5=C4C=CC=C5N(C)C)=O

• Molecular Weight:

  692.95

• References & Citations:

  [1]Zeng C, et al. Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes[J]. Molecular imaging, 2011, 10(6): 7290.2011. 00009.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1036759-00-8