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SW116 (free base)

CAT: 0804-HY-120421Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120421Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SW116 free base is a selective fluorescent ligand for sigma-2 receptor with a Ki of 14 nM. SW116 free base exhibits in methanol a maximal excitation wavelength of 333 nM, and a maximal emission wavelength of 506 nM. SW116 free base can be internalized into MDA-MB-435 cells, and reach 50% maximum fluorescent intensity in 24 minutes. SW116 free base can be as a fluorescent probe used in cancer research[1].
CAS Number
1036759-00-8
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sw116-free-base.html
Smiles
O=[S](NCCCCCCCCCCN([C@]1([H])C2)[C@@](CCC1)([H])C[C@@H]2OC(NC(C=C3C)=C(C=C3)OC)=O)(C4=CC=CC5=C4C=CC=C5N(C)C)=O
Molecular Formula
C39H56N4O5S
Molecular Weight
692.95
References & Citations
[1]Zeng C, et al. Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes[J]. Molecular imaging, 2011, 10 (6) : 7290.2011. 00009.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Sigma 1 Receptor; Sigma 2 Receptor

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