ODN INH 18
CAT:
804-HY-153840
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ODN INH 18
- CAS Number: 1934318-43-0
- UNSPSC Description: ODN INH-18 is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 showes inhibitory potency for TLR9 ligand-induced IFN-α production.
- Target Antigen: Toll-like Receptor (TLR)
- Type: Oligonucleotides
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/odn-inh-18.html
- Purity: 95.15
- Solubility: 10 mM in H2O
- Smiles: [ODN INH 18]
- Molecular Weight: 7723.29
- References & Citations: [1]Lenert P, Yasuda K, Busconi L, et al. DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo. Arthritis Res Ther. 2009;11(3):R79.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported