ODN INH-1 (sodium)

CAT:

804-HY-153841A

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UNSPSC Description: ODN INH-1 sodium is palindromic and a class R (‘restricted’) inhibitory ODN. ODN INH-1 sodium is a potent inhibitor of TLR9-induced B cells and macrophages
Target Antigen: Toll-like Receptor (TLR)
Type: Oligonucleotides
Related Pathways: Immunology/Inflammation
Applications: COVID-19-immunoregulation
Field of Research: Inflammation/Immunology
Assay Protocol: https://www.medchemexpress.com/odn-inh-1-sodium.html
Solubility: 10 mM in H2O
Smiles: [ODN INH-1 (sodium)]
References & Citations: [1]Lenert P, Yasuda K, Busconi L, et al. DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo. Arthritis Res Ther. 2009;11(3):R79. doi:10.1186/ar2710
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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