ODN INH-1

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804-HY-153841

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CAS Number: 1934318-42-9
UNSPSC Description: ODN INH-1 is palindromic and a class R (‘restricted’) inhibitory ODN. ODN INH-1 is a potent inhibitor of TLR9-induced B cells and macrophages
Target Antigen: Toll-like Receptor (TLR)
Type: Oligonucleotides
Related Pathways: Immunology/Inflammation
Applications: COVID-19-immunoregulation
Field of Research: Inflammation/Immunology
Assay Protocol: https://www.medchemexpress.com/odn-inh-1.html
Solubility: 10 mM in H2O
Smiles: [2H]O/N=I/[NH-]
References & Citations: [1]Lenert P, Yasuda K, Busconi L, et al. DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo. Arthritis Res Ther. 2009;11(3):R79. doi:10.1186/ar2710
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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