SR-3737

• UNSPSC Description:

  SR-3737 is a JNK3 and p38 inhibitor (IC50: 12 and 3 nM)[1].

• Target Antigen:

  JNK; p38 MAPK

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sr-3737.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC(OC)=C(OC)C(OC)=C1)C2=CC=CC(N3N=CC4=C3C=CC(NC5=CC=CC=C5F)=C4)=C2

• Molecular Weight:

  512.53

• References & Citations:

  [1]Kamenecka T, et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J Biol Chem. 2009 May 8;284(19):12853-61.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1164153-37-0